Disclaimer: I don't have paperbacks, so my formatting is only for digital. I have no advice for print.I make the epub in Calibre. It converts .odt directly to epub without a problem. If I need to do any editing that Calibre can't do, then I use Sigil. If Sigil can't do it, then it probably can't be done. But Calibre is much more user-friendly for me, so I prefer to use Calibre whenever possible.
I also like to name my chapters. As a reader, I've never cared for opening a new ebook and seeing a table of contents that is just a list of numbers. The numbers are important, but I want names, too. I want to see "A Short Cut to Mushrooms" or "The Scouring of the Shire" or something similar. I actually do most of this chapter stuff in the OpenOffice .odt file. I make the hyperlinks, bookmarks, and chapter breaks in OpenOffice. My advice would be to always try to do as much as you can in your word processor, because post-conversion edits can go awry sometimes. I still have to edit the table of contents in Calibre after the conversion to epub, though, and
I made a tutorial thread about how to do it.I should also add that I abandoned Microsoft Word a long time ago. Nothing but headaches for me. I hate it as a program, and I hate all the garbage code it inserts into files for its own mysterious purposes. It produces bloated files that cost more in Amazon delivery fees than an equivalent book written in OpenOffice, so in addition to all the frustration Word creates for me, it also functions as a sales tax.
I have a lot of fondness for D2D, but I don't use their epub generator.
Anyway, hope that helps. Good luck.