I use Firefox and UBlock Origin, and I also can't get past the popup. So that's probably not the magic combination.
Here are two other extensions I use:
Privacy Badger—automatically learns to block invisible trackers.
Privacy Possum— monkey wrenches common commercial tracking methods by reducing and falsifying the data gathered by tracking companies.
I also use a VPN (Surfshark), and I vary it’s location each day. Today, it had me coming in from Montreal, Canada. I’m also a Mac user.
Oh, for what it's worth,here are my UBlock Origin preferences:
Auto-update filter lists
Suspend network activity until all filter lists are loaded
Parse and enforce cosmetic filters
Ignore generic cosmetic filters
272,395 network filters + 231,164 cosmetic filters from:
My filters
0 used out of 0
Built-in
5/5
uBlock filters
5/5 46,149 used out of 46,628
uBlock filters – Ads
35,200 used out of 35,673
uBlock filters – Badware risks
8,033 used out of 8,033
uBlock filters – Privacy
589 used out of 589
uBlock filters – Quick fixes
158 used out of 163
uBlock filters – Unbreak
2,169 used out of 2,170
Ads
3/3
AdGuard – Ads
68,203 used out of 74,932
AdGuard – Mobile Ads
8,525 used out of 8,663
EasyList
69,950 used out of 71,000
Privacy
4/4
AdGuard Tracking Protection
43,376 used out of 60,516
AdGuard URL Tracking Protection
1,151 used out of 1,231
Block Outsider Intrusion into LAN
53 used out of 53
EasyPrivacy
32,274 used out of 33,168
Malware protection, security
3/3
Online Malicious URL Blocklist
3,957 used out of 3,957
Phishing URL Blocklist
91,493 used out of 91,514
PUP Domains Blocklist
189 used out of 189
Multipurpose
2/2
Dan Pollock’s hosts file
11,094 used out of 11,563
Peter Lowe’s Ad and tracking server list
3,721 used out of 3,723
Annoyances
16/16
AdGuard – Annoyances
7/7 90,284 used out of 94,119
AdGuard – Mobile App Banners
3,577 used out of 4,639
AdGuard – Other Annoyances
13,265 used out of 13,577
AdGuard – Popup Overlays
22,670 used out of 24,209
AdGuard – Social Media
20,566 used out of 21,425
AdGuard – Widgets
2,310 used out of 2,311
AdGuard/uBO – Cookie Notices
2/2
27,896 used out of 27,958
EasyList – Annoyances
7/7 73,735 used out of 78,088
EasyList – Chat Widgets
127 used out of 138
EasyList – Newsletter Notices
6,470 used out of 6,490
EasyList – Notifications
2,668 used out of 2,671
EasyList – Other Annoyances
3,847 used out of 3,978
EasyList – Social Widgets
16,176 used out of 16,199
EasyList/uBO – Cookie Notices
2/2
44,447 used out of 48,612
Fanboy – Anti-Facebook
68 used out of 68
uBlock filters – Annoyances
5,118 used out of 5,426
Regions, languages
0/36
Custom
2/2
AdGuard Annoyances filter
0 used out of 72,402
Fanboy's Annoyance List
81 used out of 93,407
Outside of the above, if it still doesn’t work for you, I have no idea why.